陈曦  教授  

劳动卫生与环境卫生学系副主任

博士生导师

研究方向：环境健康

    主持在研国家自然基金面上项目，主持完成国家自然基金青年基金、天津市科委应用基础与前沿项目、中国博士后基金等项目，荣获天津市高校中青年骨干创新人才培养计划人选，天津市“131”创新型人才培养工程第二层次人选，2022和2023年中国高被引学者。任中华预防医学会环境卫生分会委员，中华预防医学会卫生毒理分会委员，中国毒理学会工业毒理学专业委员会委员，中国环境诱变剂学会生物标志物专业委员会委员等学术委员，天津市预防医学会劳动卫生与职业病分会常委。

电子邮件:chenxi@tmu.edu.cn

学习经历

2009-2012年，天津医科大学，流行病学与卫生统计学，博士学位

2006-2009年，天津医科大学，劳动卫生与环境卫生学，硕士学位

2001-2006年，天津医科大学，预防医学专业，学士学位

工作经历

2021.01至今，天津医科大学，公共卫生学院，教授

2015.01-2020.12，天津医科大学，公共卫生学院，副教授

2015.06-2016.07，美国加州大学伯克利分校，访问学者

2012.07-2014.12，天津医科大学，公共卫生学院，讲师

主要承担或参与的课题

1. 天津市教委重点项目. 2023.01-2025.12. 在研, 主持. 2022ZD056

2. 天津市自然基金重点项目. 2023.10-2026.09. 在研, 主持. 23JCZDJC00330

3. 国家自然科学基金面上项目. 81973002. 2020.01.01-2023.12.31，已结题，主持。

4. 国家自然科学基金青年项目. 81402653，2015.1-2017.12，已结题，主持。

5. 天津市科委应用基础与前沿项目，14JCQNJC11300，2014.4-2017.3，已结题，主持。

近五年发表文章

1.Hongyue Sun#, Xi Chen#, Wenzhong Huang#, Jing Wei#, Xueli Yang, Anqi Shan, Liwen Zhang, Honglu Zhang, Jiayu He, Chengjie Pan, Jingjing Li, Jing Wu, Tong Wang, Jie Chen, Yuming Guo, Shilu Tong, Guanghui Dong*, Nai-Jun Tang*. Association between Long-Term Exposure to PM2.5 Inorganic Chemical Compositions and Cardiopulmonary Mortality: A 22-Year Cohort Study in Northern China. Environ. Health 2024, 2, 8, 530–540.

2.Qianfeng Liu, Dan Wang, Wen Li, Xiaoyu Li, Ze Yang, Ai Zhang, Jiayu He, Xu Chen, Ying Chang, Xi Chen*, Nai-Jun Tang. Association of chromosomal abnormalities with prenatal exposure to heavy metals: A nested case-control study in high-risk pregnant women in China. Ecotoxicol Environ Saf. 2023 Oct 15:265:115518.

3.Huang W#, Zhou Y#, Chen X#, Zeng X#, Knibbs LD, Zhang Y, Jalaludin B, Dharmage SC, Morawska L, Guo Y, Yang X, Zhang L, Shan A, Chen J, Wang T, Heinrich J, Gao M, Lin L, Xiao X, Zhou P, Yu Y, Tang N*, Dong G*. Individual and joint associations of long-term exposure to air pollutants and cardiopulmonary mortality: a 22-year cohort study in Northern China. Lancet Reg Health West Pac. 2023 May 4;36:100776.

4.Li X, Song F, Liu X, Shan A, Huang Y, Yang Z, Li H, Yang Q, Yu Y, Zheng H, Cao XC, Chen D, Chen KX, Chen X*, Tang NJ*. Perfluoroalkyl substances (PFASs) as risk factors for breast cancer: a case-control study in Chinese population. Environ Health. 2022 Sep 9;21(1):83.

5.Zhang A, Wang R, Liu Q, Yang Z, Lin X, Pang J, Li X, Wang D, He J, Li J, Zhang M, Yu Y, Cao XC, Chen X, Tang NJ. Breast adipose metabolites mediates the association of tetrabromobisphenol a with breast cancer: A case-control study in Chinese population. Environ Pollut. 2023 Jan 1;316(Pt 1):120701.

6.Li X, Sun X, Zhang A, Pang J, Li Y, Yan M, Xu Z, Yu Y, Yang Z, Chen X, Wang X, Cao XC, Tang NJ. Breast microbiome associations with breast tumor characteristics and neoadjuvant chemotherapy: A case-control study. Front Oncol. 2022 Sep 12;12:926920.

7.Anqi Shan#, Xi Chen#, Xueli Yang, Baoqun Yao, Fengchao Liang, Ze Yang, Fangchao Liu, Song Chen, Xiaochang Yan, Jianfeng Huang, Shaoye Bo, Nai-Jun Tang, Dongfeng Gu, Hua Yan*. Association between long-term exposure to fine particulate matter and diabetic retinopathy among diabetic patients: A national cross-sectional study in China. Environ Int. 2021 Apr 17;154:106568.

8.Wang L, Guo P, Tong H, Wang A, Chang Y, Guo X, Gong J, Song C, Wu L, Wang T, Hopke PK, Chen X*, Tang NJ*, Mao H*. Traffic-related metrics and adverse birth outcomes: A systematic review and meta-analysis. Environ Res. 2020 Sep;188:109752.

9.Anqi Shan, Ling Leng, Jing Li, Xiu-mei Luo, Ya-jiao Fan, Qiaoyun Yang, Qun-hui Xie, Yang-sheng Chen, Chun-sheng Ni, Li-ming Guo, Hua Tang, Xi Chen*, Nai-jun Tang*. TCDD-induced antagonism of MEHP-mediated migration and invasion partly involves aryl hydrocarbon receptor in MCF7 breast cancer cells. Journal of Hazardous Materials. Volume 398, 5 November 2020, 122869. doi.org/10.1016/j.jhazmat.2020.122869

10.Shan A, Zhang Y, Zhang LW, Chen X, Li X, Wu H, Yan M, Li Y, Xian P, Ma Z, Li C, Guo P, Dong GH, Liu YM, Chen J, Wang T, Zhao BX, Tang NJ*. Associations between the incidence and mortality rates of type 2 diabetes mellitus and long-term exposure to ambient air pollution: A 12-year cohort study in northern China. Environ Res. 2020 Jul;186:109551.

11.Yan M, Li C, Zhang L, Chen X, Yang X, Shan A, Li X, Wu H, Ma Z, Zhang Y, Guo P, Dong G, Liu Y, Chen J, Wang T, Zhao B, Tang NJ*. Association between long-term exposure to Sulfur dioxide pollution and hypertension incidence in northern China: a 12-year cohort study. Environ Sci Pollut Res Int. 2020 Jun; 27(17): 21826-21835.

12.Shan A#, Zhang Y, Zhang LW, Chen X, Li X, Wu H, Yan M, Li Y, Xian P, Ma Z, Li C, Guo P, Dong GH, Liu YM, Chen J, Wang T, Zhao BX, Tang NJ*. Associations between the incidence and mortality rates of type 2 diabetes mellitus and long-term exposure to ambient air pollution: A 12-year cohort study in northern China. Environ Res, 2020 Jul; 186: 109551.

13.Wang L#, Guo P, Tong H, Wang A, Chang Y, Guo X, Gong J, Song C, Wu L, Wang T, Hopke PK, Chen X*, Tang NJ*, Mao H*. Traffic-related metrics and adverse birth outcomes: A systematic review and meta-analysis. Environ Res, 2020 May 30; 188: 109752.

14.Shan A, Li M, Li X, Li Y, Yan M, Xian P, Chang Y, Chen X*, Tang NJ. BDE-47 decreases progesterone levels in BeWo cells by interfering with mitochondrial functions and genes related to cholesterol transport. Chem Res Toxicol. 2019 Feb 4. doi: 10.1021/acs.chemrestox.8b00312. [Epub ahead of print]

15.Zhang HJ, Liu YN, Xian P, Ma J, Sun YW, Chen JS, Chen X*, Tang NJ*. Maternal exposure to TCDD during gestation advanced sensory-motor development, but induced impairments of spatial learning and memory in adult male rat offspring. Chemosphere. 2018 Aug 23;212:678-686.

社会兼职

中华预防医学会环境卫生分会委员

中华预防医学会毒理分会委员 

中国毒理学会工业毒理学专业委员会委员

中国环境诱变剂学会生物标志物专业委员会委员

天津市预防医学会毒理分会委员

天津市预防医学会环境卫生分会委员

天津市预防医学会劳动卫生与职业病分会常委

ISEE Membership (International Society for Environmental Epidemiology)

《中国职业医学》编委

参编教材

职业病三级预防理论与实践. 人民卫生出版社. 2022年6月30日. ISBN：9787117332163.

二噁英类污染物的人体暴露评估. 中国环境出版社. 2016年12月. ISBN: 9787511130266.

持久性有机污染物与健康. 湖北科学技术出版社. 2019年10月. ISBN: 97875570603404.

公共卫生与预防医学（双语版）. 中国科学院教材建设专家委员会规划教材. 医学英文原版改编双语教材. 2021年3月. ISBN: 9787030657701