朱云 副教授

流行病与卫生统计学系

硕士研究生导师 

邮箱:yun.zhu@tmu.edu.cn

研究方向

1. 肿瘤精准防控

2. 营养流行病学

3. 分子流行病学

学习经历

2014年-2018年，加拿大纽芬兰纪念大学，流行病与卫生统计学专业，博士研究生/博士学位；

2010年-2014年，加拿大纽芬兰纪念大学，流行病与卫生统计学专业，硕士研究生/硕士学位；

2010年-2013年，天津医科大学，流行病与卫生统计学专业，硕士研究生/硕士学位；

2005年-2010年，天津医科大学，预防医学专业，学士学位；

工作经历 

2019年-今，天津医科大学，公共卫生学院，副教授； 

2017年-2019年，加拿大蒙特利尔大学，蒙特利尔大学医院研究中心，博士后

发表文章

1.Sijia Meng#, Chen Liu#, Keming Zhang#, Jiqiu Li, Dan Wang, Jing Zhao, Yu Wang, Meizhi Du, Chunyan Li, Yuan Wang, Wenli Lu*, Yun Zhu*. A Prebiotic-Supplemented Formula Improves Gut Microbiota and Intestinal Inflammatory Microenvironment in Patients with Colorectal Adenoma: A Double-Blind, Placebo-Controlled Trial. The Journal of Nutrition 2025. doi: 10.1016/j.tjnut.2025.09.005.

2.Jing Zhao#, Keming Zhang#, Yun Zhu*, John R. Mclaughlin, Patrick S. Parfrey and Peizhong Peter Wang*. Examining the Direct and Indirect Effects of Socioeconomic Status on Colorectal Cancer Using Structural Equation Modeling. Cancer Investigation. 2025. doi: 10.1080/07357907.2025.2570382

3.Meng Y, Yang X, Fan Y, Liu M, Zhou F, Wang Q, Lu Y, Zhu Y*, Yan H*. Association Between Hormone Levels and Retinopathy in Patients With Type2 Diabetes: A Cross-Sectional Study. Transl Vis Sci Technol. 2025:14(17).

4.Chunjie Mao, Xiaodan Zhang, Mengyu Liao, Fengqi Zhou, Xinlei Zhu, Tian Wang, Ruotian Xie, Haokun Zhang, Tiantian Yang, Kai He, Miao Guo, Yanfang Zhu, Yi Lei, Yiming Li, Ling Yao, Bohao Cui, Yuyang Miao, Han Han, Xiao Zhao, Yinting Song, Zhiyong Sun, Jinguo Yu, Wei Zhou, Yun Zhu*, Hua Yan*. Recalled Age of Myopia Onset May Predict Risk of High Adult Myopia in Chinese Adults.  Ophthalmic Research .2024, 67 (1): 266–274

5.Wang Dan#, Meng Sijia #, Li Jiqiu, Zhao Jing, Wang Yu, Du Meizhi, Wang Yuan, Lu Wenli, and Zhu Yun*. Associations of Adherence to the 2018 World Cancer Research Fund and the American Institute for Cancer Research Dietary Recommendations with Gut Microbiota and Inflammation Levels. Nutrients. 2023; 15(17):3705. 

6.Wang Yixiao#, Zhang Keming#, Dai Linna, Sun Fengya, Wang Dan, Meng Sijia, Zhao Jing, Liu Yanfang, Liu Wanting, Li Chunyan, Wang Yuan, Lu Wenli, and Zhu Yun*. Associations of fruit, whole grain, and total energy intakes with gut microbiome diversity and composition, Food & Nutrition Research. 2023; 67.

7.Du Meizhi#, Wang Yu#, Vallis Jillian, Shariati Matin, Parfrey S Patrick, Mclaughlin R John, Wang Peter Peizhong *, Zhu Yun*: Associations between polymorphisms in leptin and leptin receptor genes and colorectal cancer survival. Cancer Biol Med 2023; 20(6):438-451. 

8.Wang Yu#, Du Meizhi#, Vallis Jillian, Shariati Matin, Parfrey S Patrick, Mclaughlin R John, Wang Peter Peizhong *, Zhu Yun*: The Roles of MTRR and MTHFR Gene Polymorphisms in Colorectal Cancer Survival. Nutrients 2022; 14(21). 

9.Yun Zhu#; Jing Zhao; Jillian Vallis; Fuyan Shi; Jennifer R. Woodrow; Yujia Kong; Guangju Zhai; Patrick Parfrey; John R. McLaughlin; Peizhong Peter Wang*; Prediagnostic Consumption of Vitamin D, Calcium and Dairy Products and Colorectal Cancer Survival: Results from the Newfoundland Colorectal Cancer Registry Cohort Study, British Journal of Nutrition, 2022, 128(2): 290-299 

10.Jing Zhao#, Yun Zhu#, Meizhi Du, Yu Wang, Jillian Vallis, Patrick S. Parfrey, John R. Mclaughlin, Xiuying Qi*, Peizhong Peter Wang* Association between dietary fiber intake and mortality among colorectal cancer survivors: results from the Newfoundland familial colorectal cancer cohort study and a meta-analysis of prospective studies. Cancers.2022.

11.Cui, B.; Zhu, Y.; Zhang, X.; He, K.; Shi, Y.; Yu, J.; Zhou, W.; Zhu, Y.*; Yan, H*. Association of Physical Activity with Retinal Thickness and Vascular Structure in Elderly Chinese Population. Ophthalmic Res 2022, doi:10.1159/000527448.

12.Jingzhu Fu#; Yun Zhu#; Yue Sun; Qian Liu; Huilian Duan; Ling Huang; Dezheng Zhou; Zehao Wang; Jing Zhao; Zhenshu Li; Yue Du; Huan Liu; Fei Ma; Yongjie Chen; Changqing Sun; Guangshun Wang; Wen Li*; Guowei Huang*. Circulating Amyloid-β and Methionine-Related Metabolites to Predict the Risk of Mild Cognitive Impairment: A Nested Case-Control Study.Journal of Alzheimer's Disease, 2022, 90(1): 389-404

13.Duan H#, Sun C#, Zhu Y#, Liu Q, Du Y, Lin H, Jin M, Fu J, Ma F, Li W, Liu H, Yan J, Chen Y, Wang G, Huang G: Association of dietary habits with mild cognitive impairment among elderly in rural area of north China. Current Alzheimer Research 2021.

14.Fu J#, Liu Q#, Zhu Y#, Sun C, Duan H, Huang L, Zhou D, Wang Z, Zhao J, Li Z Ma F, Li W, Liu H, Zhang X, Chen, Y, Wang G, Du Y*, Huang G*. Circulating folate concentrations and the risk of mild cognitive impairment: a prospective study on the older Chinese population without folic acid fortification. European Journal of Neurology, 2022;6.

15.Fu J#, Liu Q#, Du Y#, Zhu Y#, Sun C, Lin H, Jin M, Ma F, Li W, Liu H, Zhang X, Chen Y, Sun Z, Wang G* and Huang G*: Age- and sex-specific prevalence and modifiable risk factors of mild cognitive impairment among older adults in China: a population-based observational study. Front Aging Neurosci 2020;12:578742.

16.Wang J#, Bai Y#, Zeng Z, Wang J, Wang P, Zhao Y, Xu W, Zhu Y*, Qi X*. Association between life-course cigarette smoking and metabolic syndrome: a discovery-replication strategy. Diabetol Metab Syndr 2022;14(1):11.

17.Cui B#, He K#, Zhang X#, Zhou W, Sun Zhi , Zhang M, Shi Y, Lei Yi, Yao L, Li Y, Liao M, Song Y, Zhao X, Han H, Zhu YF, Guo M, Zhang H, Yang T, Miao Y, Bai T, Li M , Zhang W, Yao X, Kou X, Zhu Y*, Yan H* : Association of Cigarette Smoking with Retinal Thickness and Vascular Structure in Elderly Chinese Population. Photodiagnosis Photodyn Ther 2021: 102481.

18.Qianqian Li# , Meizhi Du#, John C Knight , Yanqing Yi , Qi Wang , Peizhong Peter Wang* , Yun Zhu*.Dental Insurance Coverage,Dentist Visiting, and Oral Health Status among Asian Immigrant Women of Childbearing Age in Canada: A Comparative Study. Healthcare (Basel).2023 Oct 1;11(19):2666.

19.Li Q#, Wang Y#, Knight J, Yi Y, Wang Q, Wang PP*, Zhu Y*. Dental health status, dentist visiting, and dental insurance of Asian immigrants in Canada. International Journal for Equity in Health (2023) 22:73

20.Zhu Y, Wang PP*, Zhai G, Savas S et al: Vitamin D Receptor and Calcium Sensing Receptor Polymorphisms and Colorectal Cancer Survival in Newfoundland Population. British Journal of Cancer 2017: 117(6):898-906. 

21.Zhu Y#, Yang SR#, Wang PP*, Savas S, Wish T, Zhao J, Green R, Woods M, Roebothan B et al: Influence of pre-diagnostic cigarette smoking on colorectal cancer survival: overall and by tumour molecular phenotype. Br J Cancer 2014: 110(5):1359-66.

22.Yan J#, Zhu Y#, Cao L#, Liu Y, Zheng Y, Li W and Huang G*: Effects of maternal folic acid supplementation during pregnancy on infant neurodevelopment at 1 month of age: a birth cohort study in China.  Eur J Nutr 2019:1-12. 

23.Zhu Y, Wang PP*, Zhai G, et al. Association of rs2282679 A>C polymorphism in vitamin D binding protein gene with colorectal cancer risk and survival: effect modification by dietary vitamin D intake. BMC Cancer. 2018:18(1):155. 

24.张克明，李春燕，刘奕玮，赵菁，王奕潇，王媛，芦文丽，朱云*.结直肠癌高危人群蔬菜和红肉摄入频率与肠道菌群关系的研究.营养学报，2023,45(04):371-377.

25.张克明，孟思佳，赵菁，戴琳娜，王奕潇，王彧，杜美志，朱云*.肠道菌群与结直肠腺瘤关系的研究进展.江苏医药, 2023, 49(10): 1062-1066.

26.罗欣童，琚雅文，孟思佳，王丹，张克明，李春燕，王媛，芦文丽，朱云*.结直肠腺瘤患者中吸烟与肠道菌群和炎症关系的研究.中国微生态学杂志.2025

主要承担或参与课题

1.天津市教委/市委教育工委, 天津市特聘教授青年人才启动项目，吸烟、饮酒以及叶酸摄入量与结直肠癌发病风险之间的因果关系：孟德尔随机化研究，50万元，2021.01-2025.12，主持

2.国家自然科学基金委员会，面上项目，叶酸对结直肠癌发生的双刃剑作用及DNA胸苷酸合成机制研究（82373571）， 46万元，2024.01-2027.12，参与

3.国家自然科学基金委员会, 青年科学基金项目, WCRF-AICR抗癌饮食调节结直肠癌高危人群肠道菌群和炎症水平动态变化的随机对照试验（82003533），24万元，2021.01-2023.12, 主持

4.中国营养学会, 振东国人体质与健康研究基金，低聚半乳糖、低聚果糖与低聚异麦芽糖复合益生元干预对结直肠癌高危人群肠道菌群与炎症影响的研究（CNS-ZD2020-82）, 20万元，2021.01-2022.12, 主持

5.天津市教委社会科学重大项目，基于大数据平台的中小学生近视防控对策研究，8万元，2021.01-2022.12，参与

6.天津卫生健康科技基金，分阶段序贯功能营养治疗对儿童中重度克罗恩病的缓解作用研究（TJWJ2024MS036），10万元，2024.07-2027.06，参与

社会兼职

1.中国营养学会营养流行病分会第二届委员会，委员

2.中国抗癌协会第十届肿瘤流行病学专业委员会，委员

3.中华医学会临床流行病学和循证医学分会，青年委员

4. 中国现场统计研究会医药与生物统计分会，委员

5. 天津市健康促进与教育协会肿瘤营养专委会，副主委

6. 天津市医学会临床流行病学和循证医学专委会，委员