
李 婧 副教授
流行病与卫生统计学系
硕士研究生导师
邮箱:lijing_ph@tmu.edu.cn
研究方向
1.妊娠期糖尿病流行病学
2. 2型糖尿病流行病学
3.儿童青少年生长发育代谢流行病学
学习经历
2014~2019年,天津医科大学,流行病与卫生统计学专业,医学博士(硕博连读)
2009~2014年,天津医科大学,预防医学专业,医学学士
工作经历
2023.12-今:天津医科大学公共卫生学院 副教授
2020.10~2023.12:天津医科大学公共卫生学院 讲师
发表文章
1. Li J, Zhang R, Zhang C, Liu G, Li W, Wang H, Qiao Y, Yu Z, Hu G, Chan J, Leng J, Yang X. Effects of intensive treatment of Chinese women with gestational diabetes on the risk of offspring being overweight from 3 to 8 years of age[J]. Diabetes Obes Metab. 2024;26(9):4126-4130. DOI: 10.1111/dom.15770
2. Li J, Liu J, Zhang C, Liu G, Leng J, Wang L, Li W, Yu Z, Hu G, Chan JCN, Yang X*. Effects of lifestyle intervention of maternal gestational diabetes on offspring growth pattern before two years of age[J]. Diabetes Care. 2021;44:e42-e44. DOI: 10.2337/dc20-2750.
3. Li N#, Yang Y#, Cui D#, Li C, Ma R, Li J*, Yang X*. Effects of lifestyle intervention on long‐term risk of diabetes in women with prior gestational diabetes: A systematic review and meta‐analysis of randomized controlled trials[J]. Obes Rev. 2021;22:e13122. DOI: 10.1111/obr.13122
4. Gao M#, Cao S#, Li N, Liu J, Lyu Y, Li J*, Yang X*. Risks of overweight in the offspring of women with gestational diabetes at different developmental stages: A meta‐analysis with more than half a million offspring[J]. Obes Rev. 2021; e13395. DOI: 10.1111/obr.13395.
5. Li J, Huo X, Cao Y, Li S, Du Z, Shao P, Leng J, Zhang C, Sun XY, Ma RCW, Fang ZZ*, Yang X*. Bile acid metabolites in early pregnancy and risk of gestational diabetes in Chinese women: A nested case-control study[J]. EBioMedicine. 2018;35: 317-324. DOI: 10.1016/j.ebiom.2018.08.015
6. Huo X#, Li J#, Cao Y, Li S, Shao P, Leng J, Li W, Liu J, Yang K, Ma RCW, Hu G, Fang ZZ*, Yang X*. Trimethylamine-N-oxide metabolites in the early pregnancy and risk of gestational diabetes: a nested case control study[J]. J Clin Endocrinol Metab. 2019;104(11):5529-5539. DOI: 10.1210/jc.2019-00710.
7. Liu J#, Li J#, Yang K, Leng J, Li W, Yang W, Huo X, Yu Z, Ma R, Hu G, Fang Z, Yang X*. Ceramides and their interactive effects with trimethylamine-N-oxide metabolites on risk of gestational diabetes: A nested case-control study[J]. Diabetes Res Clin Pract. 2021,171:108606. DOI: 10.1016/j.diabres.2020.108606.
8. Liu J#, Li J#, Li S, Leng J, Li W, Yang W, Huo X, Chen L, Ma RCW, Hu G, Fang ZZ*, Yang X*. Circulating Lysophosphatidylcholines in Early Pregnancy and Risk of Gestational Diabetes in Chinese Women [J]. J Clin Endocrinol Metab. 2020,105(4):dgaa058. DOI : 10.1210/clinem/dgaa058.
9. Wang H#, Li J#, Leng J, Li W, Liu J, Yan X, Yu Z, Hu G, Ma RCW, Fang Z*, Wang Y*, Yang X*. The CDKAL1 rs7747752-Bile Acids Interaction Increased Risk of Gestational Diabetes Mellitus: A Nested Case-Control Study[J]. Front Endocrinol (Lausanne). 2022;13:808956. DOI: 10.3389/fendo.2022.808956.
10. Liu H#, Li J#, Leng J, Wang H, Liu J, Li W, Liu H, Wang S, Ma J, Chan J, Yu Z, Hu G, Li C*, Yang X*. Machine learning risk score for prediction of gestational diabetes in early pregnancy in Tianjin, China[J]. Diabetes Metab Res Rev. 2021,37(5):e3397. DOI: 10.1002/dmrr.3397.
11. Li J#, Cao Y#, Sun XY, Han L, Li SN, Gu WQ, Song M, Jiang CT, Yang X*, Fang ZZ*. Plasma tyrosine and its interaction with low high‐density lipoprotein cholesterol and the risk of type 2 diabetes mellitus in Chinese[J]. Journal of Diabetes Investigation. 2019, 10: 491-498. DOI: 10.1111/jdi.12898
12. Cao Y#, Li J#, Zhang Z#, Liu J, Sun X, Feng X, Luo H, Yang W, Li S, Yang X*, Fang Z*. Plasma levels of amino acids related to urea cycle and risk of type 2 diabetes mellitus in Chinese adults[J]. Frontiers in Endocrinology. 2019, 10: 50. DOI: 10.3389/fendo.2019.00050
13. Gao M#, Li J#, Zhang R, Li H, Li W, Zhang S, Wang P, Wang H, Fang Z, Yu Z, Hu G, Leng J, Yang X *. Serum mannan-binding lectin-associated serine proteases in early pregnancy for gestational diabetes in Chinese pregnant women[J]. Frontiers in Endocrinology. 2023, 14: 1230244. DOI: 10.3389/fendo.2023.1230244.
14. Gao M#, Li J#, Li N, Li W, Zhang S, Zhang T, Wang H, Fang Z, Yu Z, Hu G, Leng J, Yang X*. Circulating hyaluronidase in early pregnancy and increased risk of gestational diabetes in Chinese pregnant women: A nested case control study[J]. Clinica Chimica Acta. 2023, 548: 117512. DOI: 10.1016/j.cca.2023.117512
15. Li N#, Li J#, Wang H, Liu J, Li W, Yang K, Huo X, Leng J, Yu Z, Hu G, Fang Z, Yang X *. Aromatic amino acids and their interactions with gut microbiota related metabolites for risk of gestational diabetes: a prospective nested case-control study in a Chinese cohort[J]. Annals of Nutrition & Metabolism. 2023. DOI: 10.1159/000531481
主要承担或参与课题
1. 国家自然科学基金委员会,青年科学基金项目,三甲胺调控PEMT代谢通路对妊娠期糖尿病作用的临床及机制研究(82200932),2023.01- 2025.12,主持
2. 国家自然科学基金委员会, 面上项目, 基于m6A的砷及其甲基化代谢与妊娠期糖尿病的关系及Tef/Per2介导的胎盘胰岛素抵抗机制研究(82373543),2024.01-2027.12,参与
3. 科技部,国家重点研发计划课题,“肠道微生物组与药物交互作用影响疗效及安全性的分子机制”子课题二“临床药物对肠道微生物介导疾病进程的调控机制研究”(2021YFA1301202),2022.01-2026.12,参与
4. 天津市卫生健康委员会,重点学科专项,整合代谢新因素构建儿童肥胖及2型糖尿病人工智能预测模型(TJWJ2022XK008),2022.07-2025.06,参与
5. 国家自然科学基金委员会,面上项目,“肠道菌群与胆汁酸的串话在妊娠期糖尿病发病机制中的作用”(81870549),2019.01-2022.12,参与
6.科技部,国家重点研发计划课题,“2型糖尿病、糖尿病高风险和妊娠糖尿病危险因素的早期行为干预适宜技术及疗效评价研究”子课题三“妊娠糖尿病相关危险因素的控制现况、风险预测模型、干预适宜技术与管理策略研究”(2018YFC1313903),2018.09-2021.12,参与
社会兼职
1. 天津市医学会流行病学和循证医学分会第三届委员会委员
获奖
1.2023年度天津医科大学年终考核评为优秀
2.2022年度天津医科大学年终考核评为优秀
3.2021年度天津医科大学研工部兼职辅导员考核被评为优秀
4.2020-2021年度天津医科大学优秀班导师
5.2019年天津医科大学优秀毕业博士研究生
6.2018年天津医科大学研究生国家奖学金