天津医科大学徐祯，讲师

徐祯讲师

卫生毒理与卫生检验检疫学系

简历

徐祯，博士，天津医科大学讲师，担任预防医学专业必修课“防疫检验技术”“防疫检验技术实验”“卫生微生物实验”主讲教师。主持1项省级课题，1项横向课题，参与国家自然科学基金2项，发表论文论著16篇，其中以第一作者发表论文9篇，以第一作者发表论著1篇。

研究方向

1. 耐药葡萄球菌分子流行病学研究

2. 葡萄球菌耐药进化研究

3. 耐药葡萄球菌抑制靶点研究

学习经历

2005年-2009年，厦门大学，生物科学专业，理学学士

2005年-2009年，厦门大学，微生物学专业，硕士研究生/硕士学位；

2005年-2009年，伦敦玛丽女王大学，生物科学专业，博士研究生/博士学位

工作经历

2016年-今，天津医科大学，公共卫生学院，讲师

主要承担或参与的课题

1.天津市自然科学基金，源于医护人员耐甲氧西林金黄色葡萄球菌的分子流行特征研究(17JCYBJC43000)，2017.10-2020.9, 主持

2.西青科联体科研项目，ICU医护及环境来源葡萄球菌与院感发生的关联性研究 (XQYYKLT202104), 2021.10-2023.9：主持

3.基于单细胞测序技术对Pax8在碘致甲状腺肿中调控机制的研究，国家自然科学基金项目，82073549，2021.01.01-2024.12.31，53万元，参与

4. 基于Pax8通路的碘过量致甲状腺肿大机制研究，国家自然科学基金青年项目，81703218，20万，2018.1-2021.1：参与

近五年发表文章

1. Qiu M, Xu Z. Berberine hydrochloride reduces staphyloxanthin synthesis by inhibiting fni genes in methicillin-resistant Staphylococcus aureus[J]. Molecular Biology Reports, 2024, 51(1): 761.

2. Xu Z, Yuan C*. Molecular Epidemiology of Staphylococcus aureus in China Reveals the Key Gene Features Involved in Epidemic Transmission and Adaptive Evolution. Microbiology Spectrum. 2022 :e0156422.

3. Xu Z*, Chen L, Chen X, Tang A, Huang D, Pan Q, Fang Z*. Prevalence and Molecular Characterization of Methicillin-Resistant Staphylococci Recovered from Public Shared Bicycles in China. Int J Environ Res Public Health. 2022; 19（8 ）:4492. (IF: 4.614)3.

4. Liu Y, Chen L, Duan Y, Xu Z*. Molecular Characterization of Staphylococci Recovered from Hospital Personnel and Frequently Touched Surfaces in Tianjin, China. Can J Infect Dis Med Microbiol. 2022 Aug 10;2022:1061387.

5.Xu Z, Li X, Tian D, Sun Z, Guo L, Dong C, Tang N, Mkrtchyan HV. Molecular characterization of methicillin-resistant and -susceptible Staphylococcus aureus recovered from hospital personnel. J Med Microbiol. 2020 Dec;69(12):1332-1338

6.Xu Z, Cave R, Chen L, Yangkyi T, Liu Y, Li K, Meng G, Niu K , Zhang W, Tang N, Shen J, Mkrtchyan H*.Antibiotic resistance and molecular characteristics of methicillin-resistant Staphylococcus epidermidis recovered from hospital personnel in China[J]. J Glob Antimicrob Resist. 2020; doi: 10.1016/j.jgar.2020.02.013.

7. Xu Z, Chen J, Vougas K, Shah A, Shah H, Misra R, Mkrtchyan H*., Comparative Proteomic Profiling of Methicillin-Susceptible and Resistant Staphylococcus aureus. 2020, 20(2): e1900221.

8. Xu Z, Liu S , Chen L , Liu Y, Tan L, Shen J* and Zhang W. Antimicrobial resistance and molecular characterization of methicillin-resistant coagulase negative staphylococci from public shared bicycles in tianjin, china. Journal of global antimicrobial resistance. 2019, 19: 231-235

9. Xu Z, Misra R, Jamrozy D, Paterson G, Cutler R, Holmes M, Gharbia S, Mkrtchyan H*. Whole Genome Sequence and Comparative Genomics Analysis of Multi-drug Resistant Environmental Staphylococcus epidermidis ST59[J]. G3: Genes Genomes Genetics, 2018.4.23, 8:2225-2230

10. Xu Z, Shah H, Misra R, Chen J, Zhang W, Liu Y, Cutler R， Mkrtchyan H*. The prevalence, antibiotic resistance and mecA characterization of coagulase negative staphylococci recovered from non-healthcare settings in London, UK[J]. Antimicrobial Resistance & Infection Control, 2018.6.6, 7:73.

11. Xu Z, Mkrtchyan H V*, Cutler RR*. Antibiotic resistance and mecA characterization of coagulase-negative staphylococci isolated from three hotels in London, UK. Frontiers in microbiology. 2015, Volume 6, Article 947.

12.Xu Z, Xu Q, Zheng Z, Huang Y*. Kribbella amoyensis sp. nov., isolated from rhizosphere soil of a pharmaceutical plant, Typhonium giganteum Engl. International Journal of Systematic and Evolutionary Microbiology, 2012, 62(Pt 5): 1081-1085.