杨西林 教授

流行病与卫生统计学系

博/硕士研究生导师

学系主任

电子邮件: yangxilin@tmu.edu.cn

研究方向

1. 妊娠期糖尿病流行病

2. 糖尿病流行病

学习经历 

2000年-2002年，墨尔本大学，流行病与卫生统计学专业，博士研究生/博士学位；

1998年-2000年，蒙纳什大学，流行病与卫生统计学专业，博士研究生；

1988年-1991年，天津轻工业学院， 食品工程（食品营养方向），硕士研究生/硕士学位；

1980年-1983年，承德医学院，医疗系，毕业。

工作经历 

2005年-今，天津医科大学，公共卫生学院，教授； 

2011.11-天津医科大学，公共卫生学院，教授

2007.3-2011.10香港中文大学，医学院, 研究助理教授

2005.3-2007.2香港中文大学，医学院, 博士后研究员

2003.2- 2005.2香港中文大学，公共卫生学院，副研究员

1997.2-1998.1蒙纳什大学医学系, 访问研究员

1994.6-1997.1天津市食品卫生监督检验所，主管技师

1991.6-1994.5天津市食品卫生监督检验所，技师

1985.5-1988.8山西省榆次市人民医院，医师

1983.8-1985.4河北省新城县医院，医师

发表文章

1.Li N, Leng J, Zhang R, Wang H, Li W, Zhang S, Qiao Y, Li J, Yu Z, Hu G, Fang Z, Yang X. Maternal serum branched-chain amino acids in early pregnancy and offspring growth patterns from 1 year to 8 years of age. Chin Med J (Engl). 2024 Feb 26. doi: 10.1097/CM9.0000000000002967.

2.Cao W, Li N, Zhang R, Li W, Gao M, Wang H, Wang L, Qiao Y, Li J, Yu Z, Hu G, Leng J, Yang X. Diabetes Metab Res Rev. 2023 Dec 18:e3759. doi: 10.1002/dmrr.3759.

3.Li N, Li J, Wang H, Qiao Y, Li W, Gao M, Liu E, Yu Z, Hu G, Fang Z, Leng J, Yang X. Serum Sulfur-Containing Amino Acids and Risk of Maternal Gestational Diabetes and Adverse Growth Patterns in Offspring. Nutrients. 2023;15: 4089. https://doi.org/10.3390/nu15184089

4.Gao M, Wang H, Li W, Wang L, Li N, Qiao Y, Zhang T, Li J, Yu Z, Hu G, Leng J, Yang X. Maternal insulin resistance and maternal β-cell function during pregnancy for offspring overweight before 2 years of age among women with gestational diabetes. Pediatr Obes. 2023 Mar;18(3):e12995. doi: 10.1111/ijpo.12995. 

5.Li N, Li J, Wang H, Liu J, Li W, Yang K, Huo X, Leng J, Yu Z, Hu G, Fang Z, Yang X. Branched-chain amino acids and their interactions with lipid metabolites for increased risk of gestational diabetes. J Clin Endocrinol Metab. 2022;107(7):e3058-e3065. doi: 10.1210/clinem/dgac141.

6.Cao S, Li N, Zhang C, Liu J, Wang H, Leng J, Wang L, Li W, Yu Z, Hu G, Li J, Yang X. Adverse pregnancy outcomes are associated with an increased risk of postpartum prediabetes and diabetes in Chinese women with gestational diabetes. Diabetes Res Clin Pract. 2022 Mar 2;186:109817. doi: 10.1016/j.diabres.2022.109817.

7.Wang H, Li N, Chivese T, Werfalli M, Sun H, Yuen L, Hoegfeldt CA, Elise Powe C, Immanuel J, Karuranga S, Divakar H, Levitt N, Li C, Simmons D, Yang X. IDF Diabetes Atlas: Estimation of Global and Regional Gestational Diabetes Mellitus Prevalence for 2021 by International Association of Diabetes in Pregnancy Study Group's Criteria. Diabetes Res Clin Pract. 2022 Jan;183:109050. doi: 10.1016/j.diabres.2021.109050.

8.Gao M, Cao S, Li N, Liu J, Lyu Y, Li J, Yang X. Risks of overweight in the offspring of women with gestational diabetes at different developmental stages: A meta-analysis with more than half a million offspring. Obes Rev. 2022 Mar;23(3):e13395. doi: 10.1111/obr.13395.

9.Wang H, Yang W, Liu J, Leng J, Li W, Yu Z, Li J, Ma RCW, Hu G, Fang Z, Wang Y, Yang X. Serum concentrations of SFAs and CDKAL1 single-nucleotide polymorphism rs7747752 are related to an increased risk of gestational diabetes mellitus. Am J Clin Nutr. 2021 Nov 8;114(5):1698-1707. doi: 10.1093/ajcn/nqab225.

10.Li N, Li J, Zhang C, Liu G, Leng J, Liu J, Wang L, Li W, Yu Z, Hu G, Chan JCN, Yang X*. Usefulness of cut-off points of international criteria for prediction of post-partum diabetes and prediabetes among Chinese women with gestational diabetes. Diabetes Metab Res Rev. 2021 Nov;37(8):e3456. doi: 10.1002/dmrr.3456.

11.Li J, Liu J, Zhang C, Liu G, Leng J, Wang L, Li W, Yu Z, Hu G, Chan JCN, Yang X. Effects of Lifestyle Intervention of Maternal Gestational Diabetes Mellitus on Offspring Growth Pattern Before Two Years of Age. Diabetes Care. 2021 Mar;44(3):e42-e44. doi: 10.2337/dc20-2750.

12. Li N, Yang Y, Cui D, Li C, Ma RCW, Li J, Yang X. Effects of lifestyle intervention on long-term risk of diabetes in women with prior gestational diabetes: A systematic review and meta-analysis of randomized controlled trials. Obes Rev. 2021 Jan;22(1):e13122. doi: 10.1111/obr.13122.

13.Liu J, Li J, Yang K, Leng J, Li W, Yang W, Huo X, Yu Z, Cw Ma R, Hu G, Fang Z, Yang X. Ceramides and their interactive effects with trimethylamine-N-oxide metabolites on risk of gestational diabetes: A nested case-control study. Diabetes Res Clin Pract. 2021 Jan;171:108606. doi: 10.1016/j.diabres.2020.108606.

14.Li N, Liu J, Zhang C, Liu G, Leng J, Wang L, Li W, Yu Z, Hu G, Chan JCN, Yang X. Effects of lifestyle intervention during pregnancy on postpartum diabetes among Chinese women with gestational diabetes. Diabetologia. 2021 Jan;64(1):255-258. doi: 10.1007/s00125-020-05308-z.

15.Li X, Yang S, Cao C, Yan X, Zheng L, Zheng L, Da J, Tang X, Ji L, Yang X, Zhou Z. Validation of the Swedish diabetes regrouping scheme in adult-onset diabetes in China. J Clin Endocrinol Metab. 2020 Aug 18; dgaa524.  doi: 10.1210/clinem/dgaa524.  

主要承担或参与课题

1.2019-国家自然科学基金面上项目: 肠道菌群与胆汁酸的串话在妊娠期糖尿病发病机制中的作用(项目批准号：81870549)，2019.01.01-2022.12.31， 主持。

2.2018-国家重大研发计划：“2型糖尿病、糖尿病高风险和妊娠糖尿病危险因素的早期行为干预适宜技术及疗效评价研究”子课题三 “妊娠糖尿病相关危险因素的控制现况、风险预测模型、干预适宜技术与管理策略研究” (项目编号: 2018YFC1313903)，2018.09.01-2021.12.31，主持。

3.2010- International Diabetes Federation (IDF) and Lilly’s Bringing Research In Diabetes to Global Environments and Systems (BRIDGES); Project title: “A randomized translational study to examine the effects of shared care versus usual care in management of gestational diabetes in a three-tier prenatal care network in Tianjin, China” (Ref No. LT09-227), 01 July 2010 to 31 December 2013, 主持。

社会兼职

1.中华预防医学会流行病学分会，委会

2.Frontiers in Endocrinology Section of Aging, Associate Editor